For us we've never had problems using it with inverts, scaleless fish, and plants. We recommend using Fritz Paracleanse as they have the same active ingredients however the Fritz Paracleanse is a better deal.
Commonly used to treat:
For best results remove activated carbon. For each 10 gallons empty one packet directly into aquarium. (For 850mg jar, use one scoop [1 tsp] per 20 gallons) Repeat dose after 48 hours, after another 48 hours change 25% of water. 2 dosing treatments required for full treatment.
Treats 100 gallons. Comes with 10 packets that treat 10 gallons each.